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KMID : 1144020180140020092
Journal of Korean Association for Disability and Oral Health
2018 Volume.14 No. 2 p.92 ~ p.96
Valproate-induced Gingival Overgrowth : A Case Report
Song Ji-Hyeo

Lee Ko-Eun
Shin Min-Kyung
Kim Seong-Oh
Choi Byung-Jai
Choi Hyung-Jun
Abstract
Drug-induced gingival overgrowth is an abnormal increase of gingival tissues caused as a side effect of systemic medication. This report presents a severe case of valproate-induced gingival overgrowth combined with ulcerative and hemorrhagic lesions in a patient with Lennox-Gastaut syndrome. Considering the patient¡¯s limited cooperative ability, gingivectomy and excisional biopsy under general anesthesia were performed. The lesions were successfully treated without recurrence. When gingival enlargement does not subside with nonsurgical treatments, surgical procedure and excisional biopsy are to be performed. Postoperative management of oral hygiene is critical to prevent recurrence.
KEYWORD
Drug-induced gingival overgrowth, Valproate, Lennox-Gastaut syndrome, Gingivectomy
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